Christel Provaas schreef op vrijdag 20 september 2013, 14:16:
> Tineke Nolet-Verdel schreef op vrijdag 20 september 2013, 10:42:
>
>> Pergolide(=werkzame stof van Prascend) is tot nu toe het meest gangbare
>> medicijn om de ziekte te vertragen. Genezing is tot nu toe uitgesloten. Je
>> kunt nog ondersteunen met monnikspeper. (Provarium Breeding van Groene
>> Os).
>
> Wat doet monnikspeper precies in relatie tot cushing?
Ik zet hier onder even een heel stukje hier neer, waar o.a. monnikspeper (vitex agnus castus) als supplement beschreven wordt.
@ suzanne: waarschijnlijk is het hele artikel voor jou ook wel interessant. Je vroeg naar verschillende medicatiemogelijkheden.
As with many chronic diseases in the horse, specific nutrient supplementation and complementary or alternative therapies
have been recommended and used in horses with PPID. Both magnesium and chromium supplementation have been advocated for
supportive treatment of this condition. Magnesium supplementation (to achieve a dietary calcium to magnesium ratio of 2:1) has been
recommended, because magnesium deficiency seems to be a risk factor for insulin insensitivity and type-2 diabetes in humans.
Additionally, anecdotal reports suggest that supplementation may help horses with obesity-associated laminitis. Similarly, chromium
supplementation is recommended to improve carbohydrate metabolism (specifically glucose uptake) and improve insulin sensitivity in
type-2 diabetes in people, and supplementation with chromium tripicolinate has been shown to increase glucose uptake during a
glucose tolerance test in normal yearlings [24]. Over the past few years, an herbal product made from Chaste Berry has also been
advocated for treatment of PPID. Vitex agnus castus (Chaste Berry) extracts have been used medicinally for centuries for various
human female cycle disorders, and lay articles claim its therapeutic efficacy in horses with pituitary hyperplasia and other hormonal
dysfunction [25]. Ethanol extracts of the seeds are an organic source of dopamine stimulation and have been demonstrated to bind to
the D2 receptor of rat pituitary cells and inhibit prolactin secretion [26]. While it hasn’t completely stood the rigors of scientific
testing, many researchers are still looking into it as a source of treatment for PPID. Vitamin E is often supplemented as an antioxidant, and vitamin C given for immune support.
Het hele artikel is te vinden onder:
http://wolfecreekequine.drupalgardens.com/sites/wolfecreekequine.drupalgardens.com/files/Cushings%20Disease.pdf
Warboel
